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In a Phase III randomized trial of adjuvant chemotherapy using the platinum-based PELF (platinum, etoposide, leucovorin, and fluorouracil) regimen after potentially curative surgery for gastric cancer, no significant improvement in disease-free or overall survival was observed. The findings are discussed in the context of other trials and highlight the uncertainty surrounding the appropriate approach for the treatment of patients in this setting.
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Orchiectomy rates have increased and LHRH prescriptions have decreased over the past 5 years. Could this be related to Medicare reimbursement?
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The management of an isolated core needle breast biopsy reading of lobular neoplasia (LN) is controversial. Although this finding is associated with an increased risk for cancer, the current belief is that it, itself, is not a pre-malignant lesion.
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Mutations in several genes may refine prognosis in normal karyotype AML.
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Pioglitazone and heart disease; ARBs manufacturers spend millions to show the non-inferiority of their products compared to less expensive, generic ACE inhibitors; some athletes turn to growth hormone because it is difficult to detect; FDA Actions
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Here are common mistakes made by organizations performing root cause analyses (RCA), with solutions offered by Claire Davis, vice president of quality at Norwalk (CT) Hospital:
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ThedaCare's Appleton (WI) Medical Center has cut its average length of stay by 20% and improved quality, safety, and patient satisfaction by transforming the way it provides care.
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The radiology lab at Newton-Wellesley Hospital in the Boston area has nearly cut the wait time for patients in half through the implementation of a Six Sigma process improvement initiative. What's more, the program has also saved the department more than $700,000 with increased efficiency.